Research & Theory

RESEARCH & THEORY

Where Disciplines
Begin to Speak

I build bridges between disciplines. My research follows relationships among neuroscience, psychology, physiology, trauma, relational dynamics, behavior, and lived experience, bringing evidence from different fields into the same conceptual frame.

MY AREA OF SCIENCE

Interdisciplinary Systems Architecture

I begin with the observed outcome and work backward through the causal chain, tracing each layer toward the conditions that allowed the pattern to form. As the architecture emerges, I connect evidence across the sciences that touch the question rather than confining the problem to a single discipline. Then I turn the model around and move forward again, asking whether the reconstructed system can logically produce the phenomenon I began with and where its claims can be tested.

Reverse Systems MappingStart with the phenomenon. Trace backward through mechanisms, relationships, and organizing conditions until the underlying architecture becomes visible.
Systems ReconstructionReconnect the relevant sciences, then run the proposed architecture forward to examine whether it reproduces the observed pattern and generates testable predictions.
The subject changes. The method stays consistent: trace backward, connect across disciplines, reconstruct forward.

Published Research & Preprints

Conceptual work presented with its publication status clearly identified.

Published · Medical Hypotheses

Aquaporin Dysregulation and Persistent Hyperosmolar Microenvironments as a Barrier to Tissue Recovery

Medical Hypotheses · Volume 209 · April 2026 · Article 111916

A conceptual framework examining whether persistent hyperosmolar tissue microenvironments and aquaporin dysregulation may help explain barriers to tissue recovery across conditions that are often considered separately.

DOI: 10.1016/j.mehy.2026.111916
Read the Published Paper →
Preprint · SSRN · Posted August 20, 2026

Psychological Stretch Marks: A Framework for Understanding Persistent Reactive Templates

Susie Sarkozy · Independent Researcher · 43 pages

This conceptual model proposes the psychological stretch mark as a persistent reactive template that may form when environmental or psychological demands exceed an individual’s available integrative capacity. The framework focuses on the reactive trace between what happened and the adaptation that followed, and is offered as a construct awaiting validation.

DOI: 10.2139/ssrn.7319819
Read the Preprint →
THE RESEARCH PORTFOLIO

Research in Motion

My work develops in connected research programs. Each project is shown according to its current stage so published findings, preprints, manuscripts, and hypothesis-generating frameworks remain distinct.

Psychology, Trauma & Relational Systems

Research on persistent reactive patterns, family-system roles, identity formation, and the ways relational structures can continue shaping behavior after the original conditions have changed.

Under Peer Review

Forced Relational Conditioning

A three-tier framework organized around Scripting, Enforcement, and Catastrophic Script Collapse, examining coercive relational systems and the roles that maintain them.

Developing Manuscript

The System’s Architect of the FRC Family System

Examines the developmental pathway and organizing mechanisms behind the person who comes to govern and preserve the forced relational system.

Theoretical Framework

The Formless Center

Explores identity consolidation and role fluidity within enmeshed relational structures, with particular attention to mother-daughter dynamics.

Theoretical Framework

The Banished & Tethered Child

Extends the FRC model into children’s structural positions within the family and the relational mechanisms that produce tethering and banishment.

Developing Framework

Integrative Neural Repatterning

Explores integration as bringing present-day capacities into relationship with earlier experiences and persistent reactive patterns.

Hypothesis Generation

Observer-Mode Experience

Investigates passive visual observation during wakefulness, including autonomous imagery, preserved bodily awareness, allocentric perspective, and voluntary disengagement.

AI, Relationship & Human Influence

Work examining relational behavior in conversational AI, user influence, emotional adaptation, and architectures that make system capabilities answerable to explicit permission.

Submission-Ready Research Program

Relational Adaptation & Influence Audit

A structured audit program examining relational adaptation and influence across conversational AI systems through a frozen instrument, blinded transcripts, and replication-oriented documentation.

Research & Reference Implementation

Capability-Gated AI

Proposes a user-authorized architecture that connects visible AI functions to machine-enforceable permissions and tests the approach through a reference implementation.

Developing Research

The Emotional Education of AI

Part of the broader inquiry into how conversational systems interpret, respond to, and participate in emotionally meaningful human interaction.

Physiology, Tissue & Systems Biology

Hypothesis-driven work following persistent physiological states across tissue signaling, osmotic regulation, disease microenvironments, developmental sensitivity, and system-level adaptation.

Developing Research

Systemic Threat Physiology

Explores whether persistent peripheral osmotic stress may interact with central sensitization, autonomic regulation, and HPA-axis dynamics.

Developing Research

CYP1B1 & Genetic Susceptibility

Extends the hyperosmolar framework toward genetic susceptibility in rheumatoid arthritis and Sjögren’s syndrome through explicit, testable predictions.

Hypothesis Framework

The Tissue-Signal Loop

Proposes a reciprocal relationship among developmental sensitivity, repeated physiological signaling, biological memory, and later recalibration.

Theoretical Framework

Intergenerational Epigenetic Transmission & Endometriosis

Proposes a dual-source maternal and paternal epigenetic susceptibility model linking inherited stress-associated regulation to immune, inflammatory, and estrogen-related pathways in endometriosis.

Hypothesis Framework

Pathological Tissue Enmeshment in Endometriosis

Examines whether lesion persistence may involve reciprocal functional dependence between ectopic tissue and the surrounding microenvironment, with withdrawal and re-exposure proposed as a way to test whether that shared state has become self-reinforcing.

Developing Research

Persistent Physiological States

Continues the systems-level inquiry into how physiological conditions can persist beyond the initiating event and become self-maintaining.

Status matters. Projects listed here include published scholarship, preprints, manuscripts in review, developing manuscripts, and hypothesis-generating frameworks. Their placement on this page describes an active research portfolio rather than equivalent levels of empirical validation.
“The pattern often appears when the boundaries between disciplines become permeable.”SUSIE SARKOZY · INDEPENDENT RESEARCH